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Title

Chemical Composition and Biological Evaluation of the Essential Oil of Commiphora opobalsamum L.

Author-s

O A . Shaza M Al-Massarany, Fawkeya A Abbas, Betul Demirci, Kemal H C Baser, Shabana I Khan, Adnan J Al-Rehaily, Jaber S Mossa and Ehab A Abourashed

Contact lnfo

Office: Building 23; office # 2B 57

Tel.: (+9661)4677258; Fax: (+9661)4677245
email: ajalreha@ksu.edu.sa
PO Box 2457 
Riyadh 11451 
Kingdom of Saudi Arabia


Department

Pharmacognocy

Major

Pharmacognocy

citation

J Herbs Spices Med Plants 13(4):111 - 121 (2008)

Year of Publication

2008

Publisher

PMID

Sponsor

KSU

Type of Publication

Research

ISSN




URI/DOI

http://pubget.com/paper/pgtmp_9a1ef2b21530a0d681ba39470737c363

Full Text (Yes,No)

No

Key words




Abstract

The chemical composition of three essential oil samples (stored aerial parts, fresh aerial parts, and fresh flowering tops) of Commiphora opobalsamum L., obtained by hydrodistillation, was determined using GC-MS analysis. The identified constituents represented 69.5 to 84.4 percent of the total chemical compounds of the three samples. The major components were α-cadinol in the stored aerial parts, α-calacorene in the fresh aerial parts, and terpinen-4-ol in the fresh flowering tops. The essential oil from the fresh aerial parts exhibited antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, Candida glabrata, C. krusei, Cryptococcus neoformans, and Mycobacterium intracellulare. The same oil sample was non-selectively cytotoxic to four tumor cell lines: SK-MEL, KB, BT549 and SK-OV3. Weak antioxidant activity of the oil from the fresh aerial sample was demonstrated in a DPPH free-radical scavenging assay.


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